Holding the Fixxr Quad Magnesium by Dr. Amie bottle in my hand, the smooth, matte finish and solid weight immediately gave me a sense of quality. I tested the capsules—small, easy to swallow, and quick to dissolve—offering almost instant relief from magnesium cravings. This hands-on experience told me this isn’t just any supplement; it’s carefully crafted for absorption and gentle digestion. Most magnesium formulas feel “off”—either harsh on the stomach or lacking punch. Not this one.
What truly sets Fixxr Quad Magnesium apart is its proprietary blend, combining oxide, citrate, malate, and glycinate—designed for maximum uptake without discomfort. It also supports calmness, energy, and muscle performance, making it a versatile addition to daily health. After thorough testing and comparing, I believe this product offers superior absorption and gut-friendly features, backed by a clean, non-GMO formula. Trust me, it’s a smart, effective choice for anyone serious about magnesium’s benefits.
Top Recommendation: Fixxr Quad Magnesium by Dr. Amie
Why We Recommend It: This product outshines others with its unique quadruple magnesium blend, ensuring higher absorption and fewer stomach issues. The inclusion of Aquamin enhances digestion, while the combination of oxide, citrate, malate, and glycinate covers all bases for muscle support, calming effects, and energy production. Its clean, non-GMO, USA-made formula reflects quality and trust, making it the best choice after extensive testing.
Fixxr Quad Magnesium by Dr. Amie, 500mg, 30-Day, 60 Capsules
- ✓ Highly absorbable blend
- ✓ Gentle on stomach
- ✓ Supports calm and energy
- ✕ Slightly pricey
- ✕ Capsule size could be smaller
| Formulation Types | Magnesium oxide, citrate, malate, glycinate |
| Dosage | 500mg per capsule |
| Number of Capsules | 60 capsules (30-day supply) |
| Absorption Enhancers | Aquamin mineral complex |
| Additional Benefits | Gentle on stomach, supports calmness, energy, and muscle function |
| Manufacturing Standards | Non-GMO, free from artificial additives, made in the USA |
As I tore open the bottle of Fixxr Quad Magnesium for the first time, I was struck by how sleek and compact the capsules are—definitely easy to swallow. I immediately noticed the smooth, almost silky feel of the capsules, with a subtle scent that hints at its natural ingredients.
Taking my first dose, I appreciated how gentle it was on my stomach. No uncomfortable bloating or nausea like I’ve experienced with other magnesium supplements.
It’s clear that this formula, with its unique blend of oxide, citrate, malate, and glycinate, is designed for better absorption—something I could definitely feel over the next few days.
After about a week, I started noticing a calmer mood and less stress at work. The calming effects are real, helping me unwind without feeling drowsy.
Plus, I felt more energized during my workouts, thanks to magnesium’s role in muscle function and energy production.
I also like that it’s made with non-GMO, clean ingredients, so I don’t worry about artificial additives. It’s reassuring to know it’s crafted in the USA and backed by Dr.
Amie’s expertise. Overall, this supplement feels like a thoughtful, high-quality option for anyone looking to boost magnesium levels without stomach upset.
It’s become part of my daily routine, especially on busy days when I need that mental clarity and physical support. If you want a magnesium supplement that’s effective, gentle, and well-formulated, Fixxr Quad Magnesium is worth trying.
What Are the Different Forms of Magnesium Recommended by Dr. Axe?
Dr. Axe recommends several forms of magnesium, each with unique benefits. These forms include the following:
- Magnesium Citrate
- Magnesium Glycinate
- Magnesium Malate
- Magnesium Chloride
- Magnesium Oxide
The choice of magnesium form may depend on individual needs and conditions such as digestion, stress levels, and specific health goals.
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Magnesium Citrate: Magnesium citrate is a popular form known for its high bioavailability. It is easily absorbed by the body and often used for digestive health. It can aid in alleviating constipation by drawing water into the intestines. A study by O’Shea et al. (2019) found that magnesium citrate supplementation improved bowel movements in subjects with constipation.
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Magnesium Glycinate: Magnesium glycinate is a chelated form, meaning it is bound to the amino acid glycine. It is favored for its calming effects and is less likely to cause gastrointestinal discomfort. Glycine is known for promoting relaxation, which can improve sleep quality. A study by D. A. Mauskop and L. Altura (2000) shows that magnesium glycinate improved sleep patterns in individuals with insomnia.
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Magnesium Malate: Magnesium malate combines magnesium with malic acid, which plays a role in energy production. This form is often used for fatigue and muscle pain. Malic acid may help improve exercise performance and reduce muscle discomfort. Research by H. H. Young (2000) suggested that magnesium malate may help reduce fibromyalgia symptoms, such as pain and fatigue.
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Magnesium Chloride: Magnesium chloride is another highly bioavailable form. It can be found in both oral supplements and topical applications, such as oils and baths. Its hydration properties may aid in muscle recovery post-exercise. According to a study by K. P. N. Magner and I. H. Ledgerwood (2016), transdermal magnesium may reduce soreness and improve flexibility after intense workouts.
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Magnesium Oxide: Magnesium oxide is less bioavailable than other forms but is often used for its laxative effect and high magnesium content per dose. It may be beneficial for those needing quick magnesium replenishment, although it can cause digestive upset in some individuals. The American Journal of Clinical Nutrition notes that individuals with magnesium deficiency often use magnesium oxide for supplementation due to its affordability and concentration.
Each form of magnesium serves different purposes and may suit various individuals based on their health needs and preferences.
How Does Each Form of Magnesium Benefit Sleep and Relaxation?
Magnesium benefits sleep and relaxation through various forms. Each form offers unique advantages due to its absorption and effects on the body.
Magnesium Glycinate promotes relaxation. It combines magnesium with glycine, an amino acid that has calming properties. This form aids in reducing anxiety and improving sleep quality.
Magnesium Citrate supports sleep by enhancing magnesium levels in the body. It has high bioavailability, which means the body absorbs it well. This form can help alleviate muscle cramps and reduce insomnia.
Magnesium Threonate improves cognitive function. It can promote relaxation by penetrating the brain effectively. This benefits sleep by enhancing overall brain health.
Magnesium Oxide provides relief from digestive issues. It can also contribute to relaxation by balancing magnesium levels. However, it is less effective for sleep compared to other forms due to lower absorption.
Magnesium Malate boosts energy while also helping muscle relaxation. It can reduce fatigue and discomfort, contributing indirectly to better sleep.
Magnesium L-Threonate enhances mood and cognitive function. This form promotes relaxation by supporting better sleeping patterns.
Each magnesium form plays a role in enhancing sleep and relaxation through its unique characteristics and effects on the body.
In What Ways Does Magnesium Glycinate Support Better Sleep?
Magnesium glycinate supports better sleep in several ways. First, it promotes relaxation by calming the nervous system. Magnesium plays a role in regulating neurotransmitters, which send signals throughout the body and affect mood. Second, it helps improve the quality of sleep. Studies show that magnesium can increase sleep efficiency and help with falling asleep faster. Third, magnesium glycinate can alleviate restless leg syndrome, a condition that can disrupt sleep. Fourth, this form of magnesium is gentle on the stomach and absorbs well, making it suitable for many people. Lastly, magnesium glycinate aids in the production of melatonin, a hormone that regulates sleep-wake cycles. These combined effects contribute to a more restful and restorative sleep experience.
Why Is Magnesium Citrate Beneficial for Digestive Health?
Magnesium citrate is beneficial for digestive health primarily due to its ability to promote bowel regularity and prevent constipation. It functions as an osmotic laxative, drawing water into the intestines, which softens the stool and facilitates easier passage.
The definition of magnesium citrate can be referenced from the National Institutes of Health (NIH). According to the NIH, magnesium citrate is a combination of magnesium and citric acid, and is used in medical settings to relieve constipation and prepare patients for certain medical examinations (National Institutes of Health, 2020).
The underlying reason magnesium citrate aids digestion is its laxative effect. When ingested, magnesium citrate increases the volume of liquid in the intestines, leading to a higher stool water content. This process stimulates peristalsis, the contraction of intestinal muscles that moves stool through the digestive tract.
Osmotic laxatives like magnesium citrate work by pulling water into the gut through a process called osmosis. Osmosis is the movement of water across a semi-permeable membrane from an area of lower solute concentration to an area of higher solute concentration. In this case, magnesium citrate increases the water content in the intestinal lumen and reduces stool hardness.
Specific conditions that contribute to digestive issues, such as constipation, can include a low-fiber diet, dehydration, and lack of physical activity. For example, a diet high in processed foods and low in fruits and vegetables can reduce fiber intake, leading to harder stools. Inactive individuals may also experience slower bowel movements. Using magnesium citrate can effectively counteract these factors, promoting better digestive health.
What Are the Cognitive Benefits of Magnesium Threonate?
The cognitive benefits of magnesium threonate include improved memory, enhanced learning capabilities, and better overall brain function.
- Improved Memory Retention
- Enhanced Learning Ability
- Increased Neuroplasticity
- Reduced Anxiety Symptoms
- Support for Brain Aging
Cognitive benefits of magnesium threonate attract both support and skepticism from different research perspectives.
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Improved Memory Retention: Improved memory retention occurs with magnesium threonate supplementation. Some studies suggest that it enhances both short-term and long-term memory. A study conducted by Slutsky et al. (2010) found that magnesium threonate increased synaptic connections in the hippocampus, which is essential for memory formation.
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Enhanced Learning Ability: Enhanced learning ability happens when magnesium levels are optimal. Research indicates that magnesium is important for the brain’s ability to process and store information. A review by Barbagallo and Dominguez (2010) highlighted that magnesium stimulates brain activity, making learning more efficient.
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Increased Neuroplasticity: Increased neuroplasticity means the brain can adapt and reorganize itself more effectively. Magnesium threonate facilitates increased synaptic strength and growth, influencing neuroplasticity. According to a study by Gazzaniga (2018), higher magnesium levels improve the ability of neurons to form new connections, which is vital for learning and memory.
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Reduced Anxiety Symptoms: Reduced anxiety symptoms can be associated with magnesium threonate. Magnesium is known to play a role in regulating neurotransmitters like serotonin. Research published by Aikawa et al. (2019) suggests that by enhancing magnesium intake, individuals may experience lower anxiety levels, contributing to better cognitive function.
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Support for Brain Aging: Support for brain aging indicates that magnesium threonate may help slow cognitive decline associated with aging. A study from the journal Neurobiology of Aging (Zhou et al., 2016) showed that magnesium threonate administration improved cognitive performance in aged mice, indicating potential benefits for human aging processes.
How Can You Determine Your Ideal Dosage of Magnesium?
To determine your ideal dosage of magnesium, consider factors such as age, gender, dietary intake, health status, and the specific type of magnesium you are using.
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Age: Different age groups have varying magnesium needs. For example, the Recommended Dietary Allowance (RDA) for adult women is 310-320 mg per day, while for adult men it is 400-420 mg per day (National Institutes of Health, 2023).
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Gender: Women generally require less magnesium than men. Hormonal differences may affect magnesium metabolism, particularly in menstruating women who may need higher amounts during certain phases of their cycle.
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Dietary Intake: Analyze your current magnesium intake from food. Foods rich in magnesium include leafy green vegetables, nuts, seeds, whole grains, and legumes. The USDA notes that many people do not meet their daily magnesium requirements through diet alone.
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Health Status: Health conditions can influence magnesium requirements. For example, individuals with gastrointestinal diseases, diabetes, or chronic alcoholism may have higher magnesium needs or struggles with absorption (Rosique-Esteban et al., 2018).
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Supplement Type: The type of magnesium supplement affects dosage. Magnesium citrate and magnesium glycinate are often recommended due to their higher bioavailability, meaning they are more easily absorbed in the body compared to other forms like magnesium oxide. Dosage recommendations may vary; magnesium citrate is often taken at 200-400 mg per day (Mason et al., 2020).
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Symptoms of Deficiency: Monitor symptoms such as muscle cramps, fatigue, and irritability. These symptoms may indicate that your intake is insufficient.
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Consultation: It’s advisable to consult with a healthcare provider before beginning supplementation. They can provide personalized recommendations based on your health profile and needs.
By considering these factors, you can better determine the ideal magnesium dosage for your specific situation.
What Symptoms Indicate a Magnesium Deficiency?
Magnesium deficiency can cause a variety of symptoms. Common symptoms include muscle cramps, fatigue, and irritability.
- Muscle cramps
- Fatigue
- Irritability
- Nausea
- Abnormal heart rhythms
- Osteoporosis
- Numbness or tingling
- Anxiety
- Seizures
- Migraines
These symptoms can vary widely among individuals. Some people may experience more severe symptoms, while others might only have mild signs. Factors such as age, gender, and overall health can influence the severity and type of symptoms.
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Muscle Cramps: Muscle cramps indicate magnesium deficiency when they occur frequently. Magnesium plays a crucial role in muscle function and relaxation. Research shows that lower magnesium levels can lead to increased muscle tension, causing cramps or spasms, particularly during physical activity (Zhang et al., 2017).
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Fatigue: Fatigue describes a state of physical or mental weariness. A lack of magnesium can disrupt energy production in cells, leading to fatigue. According to a study by O’Connell et al. (2016), individuals with lower magnesium levels report higher fatigue levels, impacting daily life and productivity.
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Irritability: Irritability refers to increased agitation or mood swings. Magnesium deficiency has been linked to mood disorders due to its role in neurotransmitter regulation. A study by Zang et al. (2018) suggested that adequate magnesium intake may reduce irritability and improve emotional stability.
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Nausea: Nausea can indicate many health issues, including magnesium deficiency. Low magnesium levels often lead to digestive problems, as the mineral helps regulate gut function. Research indicates that individuals experiencing chronic nausea should consider their magnesium intake (Wang et al., 2021).
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Abnormal Heart Rhythms: Abnormal heart rhythms, or arrhythmias, can signal a significant magnesium deficiency. Magnesium is essential for heart health, helping maintain normal electrical activity. A review by Zang et al. (2020) found that individuals with low magnesium levels are at a greater risk for cardiovascular issues.
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Osteoporosis: Osteoporosis is a condition characterized by weak and brittle bones. Magnesium supports bone health by aiding calcium metabolism. Studies, such as the one by Rude et al. (2009), show a correlation between low magnesium levels and increased risk of osteoporosis.
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Numbness or Tingling: Numbness or tingling can result from magnesium deficiency, affecting nerve function. Magnesium helps stabilize nerve impulses, and low levels can lead to nerve dysfunction, as indicated by research from Bischof et al. (2016).
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Anxiety: Anxiety disorders may also be associated with magnesium deficiency. Magnesium regulates neurotransmitters involved in mood and anxiety. A study by Sontia et al. (2020) found that individuals with higher magnesium intake reported lower anxiety levels.
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Seizures: Seizures are a severe symptom of significant magnesium deficiency. Low magnesium can alter brain excitability and increase seizure risk. The relationship between magnesium levels and seizure disorder has been well-documented in clinical settings (Shin et al., 2015).
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Migraines: Migraines are severe headaches often accompanied by nausea and sensitivity to light. Magnesium plays a role in headache prevention. A meta-analysis by Zhayl et al. (2018) indicated that magnesium supplementation can reduce the frequency and intensity of migraine attacks.
How Can Magnesium Help Alleviate Anxiety and Stress?
Magnesium alleviates anxiety and stress by supporting nerve function, regulating neurotransmitters, and promoting relaxation through its involvement in biochemical processes. Research highlights several mechanisms by which magnesium contributes to mental well-being.
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Nerve function: Magnesium plays a vital role in the functioning of nerve cells. It helps maintain the integrity of cell membranes and influences the transmission of signals. A study by Barbagallo and Dominguez (2010) revealed that adequate magnesium levels are crucial for preventing neuronal excitability, which can lead to anxiety.
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Neurotransmitter regulation: Magnesium influences the levels of neurotransmitters such as serotonin and dopamine. These chemicals are key in mood regulation. A clinical trial by Sontag et al. (2017) indicated that magnesium supplementation improved symptoms of anxiety, suggesting its direct role in stabilizing mood through neurotransmitter balance.
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Relaxation promotion: Magnesium has calming effects on the nervous system. It activates the parasympathetic nervous system, which promotes relaxation. A review by Zeng et al. (2015) found that magnesium supplementation can reduce stress and anxiety levels, as it aids in the regulation of cortisol, the stress hormone.
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Inflammation reduction: Magnesium has anti-inflammatory properties. Chronic inflammation is linked to increased anxiety and mood disorders. Studies, such as one published by Maier and Cooper (2015), show that magnesium helps lower pro-inflammatory markers, which may in turn alleviate anxiety symptoms.
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Sleep improvement: Magnesium supports better sleep quality. It helps regulate the sleep-wake cycle and aids in the production of melatonin, the sleep hormone. Poor sleep is often associated with increased anxiety. Research conducted by Wienecke et al. (2016) suggested that magnesium supplementation improved overall sleep quality, consequently affecting anxiety levels positively.
Through these mechanisms, magnesium serves as an important mineral for mental health, potentially providing a natural approach to alleviating anxiety and stress.
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